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Notes Search Results Slide Text Learn More To watch this video, use the preview feature in Storyline 360, upload your published output to a server, publish to Review 360, or switch to static video quality. Streaming video is unavailable for local playback. Hide captions (Ctrl+Alt+C) Show captions (Ctrl+Alt+C) Enter full-screen (Ctrl+Alt+F) Exit full-screen (Ctrl+Alt+F) Mute (Ctrl+Alt+M) Next (Ctrl+Alt+.) Pause (Ctrl+Alt+P) Play (Ctrl+Alt+P) Playback speed Previous (Ctrl+Alt+,) Replay (Ctrl+Alt+R) Search Settings Submit (Ctrl+Alt+S) Unmute (Ctrl+Alt+M) Autoscroll Close Transcript Move window Open Resize window Resume autoscroll Select track Show timestamps Transcripts Options cross contamination carry over start start start start carry over feed is transferred into an unacceptable one cross contamination processing, handling or delivery good manufacturing practices sequencing flushing cleaning carry over is a form of cross contamination that happens when a substance from an acceptable location or feed is transferred into an unacceptable one. it usually takes place during feed processing, handling or delivery. good manufacturing practices are fundamental to avoid carry over and, depending on the substance used, they can include sequencing, flushing and cleaning feed processing equipment. x bulk truck error in bin chart records incomplete clean-out bridging and hang-up x bins bridging residual feed from incomplete clean-out x elevators residual feed remaining in buckets and boot electrostatic or moisture hang-up x conveyors incomplete clean-out electrostatic or moisture hang-up x surge bin incomplete clean-out electrostatic or moisture hang-up x mixer residual feed remaining in mixer build-up of material on ribbon and walls electrostatic hang-up on walls and top leaking mixer gate (not fully closed) x dust system delayed return of dust to production line excessive pick-up of drug and carrier hang-up (electrostatic or moisture) carry over and equipment adjust for more complete clean-out remodel bin or discharge adjust ribbons or paddles remodel discharge for more complete clean-out add drug when mixer is ½ to ¾ full adjust air velocity at collection points allow more time for dust to clear system use liquid ingredient to reduce dustiness collect and discard dust following production of medicated feeds remodel dust system ground wire to affected equipment purchase non-electrostatic form of premix use liquid ingredient to retain dust vibrators to shake hang-up loose how to correct our processes? electrostatic hang-up electrostatic hang-up delayed or extended dust return delayed or extended dust return mixer residues mixer residues surge bin, conveyor residues surge bin, conveyor residues corrective actions don’t match the mode of carry over. please try again. incorrect try again try again try again try again elevator residues bin residues entire system it seems that some of your answers are still incorrect. please take a moment to review your answers. incorrect continue continue continue continue adjust bucket clearance in boot install air sweep jets remodel boot for more complete clean-out manual inspection and cleaning when changing kind of feed stored install vibrator or air sweep jets use production scheduling allow time between kinds of feed for manual cleaning of system use flush material establish clean out procedure for truck analyze delivery samples randomly bulk truck well done! by following these practices you can ensure avoiding carry over. continue continue continue continue correct submit submit submit cross contamination adjust bucket clearance in boot install air sweep jets remodel boot for more complete clean-out manual inspection and cleaning when changing kind of feed stored install vibrator or air sweep jets use production scheduling allow time between kinds of feed for manual cleaning of system use flush material establish clean out procedure for truck analyze delivery samples randomly elevator residues bin residues entire system bulk truck cuáles es la respuesta correcta? en el ppt no está. avoiding carry over sequencing sequencing sequencing sequencing flushing flushing flushing flushing equipment clean-out equipment clean-out equipment clean-out equipment clean-out feed mills multiple species increased risk of cross contamination sequencing sequence in order determines carry over likehood substance x substance x substance x substance x + level - level in this process, it is imperative that feed production records are kept and that they are detailed enough to denote the last batch. ! flushing eliminate residues the amount of flush material depends on the system flushing characteristics based on abrasion. cannot contaminate the next product. should not adhere to the walls. easy flow. sufficient quantity. enough time for cleaning. cheap – not always can be reutilized. equipment clean-out potentially the most effective method of avoiding carry over high potency drug sequencing cannot be incorporated feed processing systems physical properties of drugs it seems that some of your answers are still incorrect. please take a moment to review the right answers. try again try again try again try again incorrect it seems that some cleaning operation is needed in one or more of your answers. please try again. incorrect correct answer correct answer correct answer correct answer well done! by following the right order you can ensure avoiding carry over. continue continue continue continue correct carry over if the first product to be manufactured is product y , the following can be product z with monesin. if the first product to be manufactured is product 2 (containing copper), the following can be product w for horses. if the first product to be manufactured is product y, the following can be product w for horses. if the first product to be manufactured is product w for horses, the following can be product x (with copper). yes no carry over if the first product to be manufactured is product y , the following can be product z with monesin. if the first product to be manufactured is product 2 (containing copper), the following can be product w for horses. if the first product to be manufactured is product y, the following can be product w for horses. if the first product to be manufactured is product w for horses, the following can be product x (with copper). submit submit submit yes no suggestion suggestion suggestion date and description of the test: objective; acceptance criteria; residue to be removed; description of procedure; flushing material used; method of analysis used to determine the residues; results obtained; conclusion. adjust the procedure to the required results; test again; validate the procedure. flushing material – type, quantity; flushing time; quantity of undesirable residue to be removed; analysis of residual substance; segregation of flushing material. validation planning planning planning execution execution execution reporting reporting reporting summary define carry over identify when and how it can happen apply good manufacturing practices to ensure feed safety cross contamination carry over 2 2 2 3 3 3 4 4 4 5 5 5 6 6 6 6.1 6.1 6.1 6.1 6.2 6.2 6.1 6.3 6.3 7 7 7 8 8 8 9 9 9 10 10 10 check previous previous congratulations! you have finished module. congratulations! you have finished module. <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text="Welcome to the Global Animal Nutrition Programme: Carry Over module!"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Carry over is a form of cross contamination that happens when a substance from an acceptable location or feed is transferred into an unacceptable one. It usually takes place during feed processing, handling or delivery. 
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Good Manufacturing Practices are fundamental to avoid carry over and, depending on the substance used, they can include sequencing, flushing and cleaning feed processing equipment. "> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#C00000" BulletFont="Arial" /> </Style> <Span Text="To effectively prevent carry over, you should be aware of the different ways equipment can be contaminated during the manufacturing process.
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#C00000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#C00000" BulletFont="Arial" /> </Style> <Span Text="Click each icon to learn about the different types of contamination. "> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Once you have identified the origin of contamination, you can take appropriate corrective actions to address them. 
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text="Let’s see some examples. Click on each of the most commonly seen situations to reveal corrective actions for them."> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Now it’s your turn to address carry over!
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text="Drag and drop the different locations in which carry over can occur to the corrective actions to address them. Then, click Submit to review your answer."> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Feed mills that produce for multiple species experience an increased risk of cross contamination with medicated feed additives and other ingredients. But there are many ways to avoid carry over: sequencing, flushing and equipment clean-out. 
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Click each method to learn more about it."> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="The ordering sequence determines the likelihood of carry over and tissue residue. Make sure you schedule the production of all feed having the same substance in sequence. Also ensure they have the higher levels first and the lower level at the end.
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#404040" BulletFont="Arial" /> </Style> <Span Text="In this process IT is imperative that feed production records are kept and that they detailed enough to denote the last batch.
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <BaseSpanStyle FontFamily="Calibri" FontSize="18" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" ForegroundColor="#000000" /> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text=""> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Multiple" LineSpacing="21" SpacingBefore="0" SpacingAfter="8"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Flushing objective is to eliminate the residues of an active ingredients, medicated feed and other substances. It involves taking a known ingredient and moving a quantity through the system to flush out the substance that remains. The amount of flush material depends on the system. 
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Flushing materials must be abrasive enough to remove waste. However they cannot contaminate the next product. They must be inert and not react with them.
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="In addition, flushing materials should flow with ease. They must be used in sufficient quantity to draw the adhered debris into the equipment and circulate for a sufficient time for the removal of the waste. 
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="We may not"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> <Span Text=" "> <Style FontSize="11" FontIsBold="True" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> <Span Text="always be able to reuse them, so they should have an appropriate cost. 
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <BaseSpanStyle FontFamily="Calibri" FontSize="18" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" ForegroundColor="#000000" /> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text=""> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Equipment clean-out is potentially the most effective method of avoiding carry over during feed processing. Cleaning the whole system to remove residues is recommended under high risk situations like:
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="45" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" ListLevel="0" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="Bullet" ListTypeFormat="Plain" Color="#000000" BulletChar="·" BulletFont="Symbol" /> </Style> <Span Text="Working with a high potency form of a drug;
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="45" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" ListLevel="0" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="Bullet" ListTypeFormat="Plain" Color="#000000" BulletChar="·" BulletFont="Symbol" /> </Style> <Span Text="Sequencing cannot be incorporated into the production schedule; 
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="45" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" ListLevel="0" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="Bullet" ListTypeFormat="Plain" Color="#000000" BulletChar="·" BulletFont="Symbol" /> </Style> <Span Text="Feed processing systems have large carry over between batches;
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="45" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" ListLevel="0" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="Bullet" ListTypeFormat="Plain" Color="#000000" BulletChar="·" BulletFont="Symbol" /> </Style> <Span Text="Physical properties of drugs are such that sequencing and flushing are not sufficient to prevent carry over."> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Now that you have learned how to avoid carry over, try to identify when a cleaning operation is needed.
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="First, review the following product sequences that will go through the same processing machine in sequence. Then click the Compatibility Chart icon on screen to review the acceptable product sequences and select the ones that are safe.
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text="When you are ready, click Submit to review your answer. "> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Prevention of carry over procedures should be validated to demonstrate their efficacy in removing undesired residues. This process includes three main steps:
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Planning
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Execution
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Reporting
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" Color="#000000" BulletFont="Arial" /> </Style> <Span Text="Click each step to explore the main events that take place in each one.
"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <BaseSpanStyle FontFamily="Calibri" FontSize="12" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" ForegroundColor="#000000" /> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text=""> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" CustomTabStops="" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text="You have reached the end of this module. By now you should be able to define carry over, identify when and how it can happen and apply good manufacturing practices to ensure feed safety."> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document> <Document xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"> <Content> <Block> <Style FlowDirection="LeftToRight" LeadingMargin="0" TrailingMargin="0" FirstLineMargin="0" Justification="Left" LineSpacingRule="Single" LineSpacing="20" SpacingBefore="0" SpacingAfter="0"> <ListStyle ListType="None" ListTypeFormat="Parentheses" BulletFont="Arial" /> </Style> <Span Text="Thank you for taking this course!"> <Style FontSize="11" FontIsBold="False" FontIsItalic="False" FontIsUnderline="False" FontIsStrikeout="False" /> </Span> </Block> </Content> </Document>